Monday, 6 June 2016

Hypertension at a glance: Introduction & Treatments

Hypertension is covered in Cardiovascular System module, Semester 2, Bachelor of Pharmacy in IMU.

First,we must know what hypertension (HPN) is.
These notes are based on Dr.Subrat lecture slides. When comes to studying I prefer to use mind map and tables.

Introduction:
Before that, let us revise what are the functions of some adrenergic receptors. Familiar with these receptors is definitely going to help us in understanding the mechanism of HPN and its pharmacological treatments.


It is the best if you can memorise this! In higher semester you are going to deal with these too. OK lets us move on to HPN.


 Hypertension (HPT) is defined as persistent elevation of SBP of > 140mm Hg and / or DBP of > 90mm Hg.




This is the simple outline of introduction of hypertension. 
The risk factors and effects are pretty easy to understand. The risk factors for primary hypertension include overweight, smoking, alcohol, sedentary lifestyle etc. Hypertension cause damage to arteries and increase the risk of getting other diseases.

RAAS stands for Renin-Angiotensin Aldosterone system. There are plenty of information on internet about this system. As a student, you must understand and remember this mechanism well, as this will help you in the following semester.
source: google image


I think this summarises the introduction of hypertension. Wow it really take a lot of time to type this up.  

Overview of the pharmacological treatment:


1. Drugs act on RAAS: click me
2. Drugs act on sympathetic nervous system: poke here!!
3.Diuretics:Diuretics
4.Calcium Channel Blockers: Cardiac muscles and CCB
5. Vasodilators: http://louisastudy129.blogspot.my/2016/06/antihypertensive-treatmentvasodilator.html

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